Detalhe da pesquisa
1.
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Cell
; 184(3): 655-674.e27, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497611
2.
Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.
Cell
; 156(4): 786-99, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24529380
3.
An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress.
Mol Cell
; 81(16): 3275-3293.e12, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34245671
4.
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Mol Cell
; 81(13): 2705-2721.e8, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33974911
5.
mTORC1 activity negatively regulates human hair follicle growth and pigmentation.
EMBO Rep
; 24(7): e56574, 2023 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37212043
6.
eIF4A inactivates TORC1 in response to amino acid starvation.
EMBO J
; 35(10): 1058-76, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26988032
7.
Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor.
Aging Cell
; 22(8): e13888, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37222020
8.
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor.
Nat Cell Biol
; 25(9): 1303-1318, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37563253
9.
Codependencies of mTORC1 signaling and endolysosomal actin structures.
Sci Adv
; 9(37): eadd9084, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703363
10.
Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements.
J Biol Chem
; 286(44): 38768-38782, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21896491
11.
A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids.
Nat Cell Biol
; 24(9): 1394-1406, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36097072
12.
Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity.
Nat Aging
; 2(9): 796-808, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118503
13.
The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging.
Front Aging
; 2: 707372, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35822019
14.
GRASPing the unconventional secretory machinery to bridge cellular stress signaling to the extracellular proteome.
Cell Stress
; 5(11): 173-175, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34782889
15.
The LMP1 promoter can be transactivated directly by NF-kappaB.
J Virol
; 83(10): 5269-77, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19279104
16.
Author Correction: A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids.
Nat Cell Biol
; 25(2): 366, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36536178
17.
CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc.
Dev Cell
; 42(4): 376-387.e5, 2017 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28829945
18.
Functional characterization of hepatocyte nuclear factor-4 alpha dimerization interface mutants.
FEBS J
; 273(9): 1948-58, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16640558
19.
Lysosomal recruitment of TSC2 is a universal response to cellular stress.
Nat Commun
; 7: 10662, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26868506
20.
TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1.
Sci Rep
; 5: 13828, 2015 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26345496